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Gragert Lab at Tulane Cancer Center

Population Genetics and Informatics for Transplantation

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Software

 

TransplantToolbox – HLA Tools for Solid Organ Transplant

  •   ALLAN – Convert IMGT/HLA Allele data to UNOS Antigen Equivalents 

  •  VICTOR– Computes virtual crossmatch probabilities for molecular HLA typing data of donors

  •  CPRA-Allele – Calculated Panel Reactive Antibody (CPRA) Calculation – Measures transplant candidate sensitization for kidney allocation using NMDP population genetic HLA reference panel

Be The Match Bioinformatics Research Resources for Hematopoietic Stem Cell Transplantation

  • HapLogic and the HLA Matching Algorithm for Stem Cell Transplantation

  • HaploStats – Interprets an HLA typing in the context of population haplotype frequencies

GitHub Public Repositories

  • ALLAN 

  • VICTOR

Recent Activities

  • Updated CPRA Calculation Released to Production
  • ABO-adjusted cPRA – Improving Equity in Kidney Transplantation Among Candidate ABO Blood Groups
  • ASHI2020 Abstract on HLA Antibody Markup Language (HAML) Integration
  • ASHI2020 Workshop on Allocation Disparities
  • Stem cell donor HLA typing improves CPRA in kidney allocation

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