Prototype 11-Locus CPRA Calculator based on NMDP HLA Genotype Frequencies

We are happy to announce public availability of a new web tool for measuring HLA antibody sensitization, available as part of our TransplantToolbox.

This calculated panel reactive antibody (CPRA) calculator includes all classical HLA loci and supports any combination of unacceptable antigens represented as IMGT/HLA two-field alleles and UNOS antigens.

The reference panel is based on a large HLA-typed cohort of volunteer donors from National Marrow Donor Program (NMDP). 

Please test out our NMDP CPRA calculator here and provide feedback!

We also provide a web services interface here for programming integration.