Publications

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Original Research Articles:

  • Schmauch E, Piening B, Xia B, Zhu C, Stern J, Zhang W, Dowdell A, Loza B-L, Mohebnasab M, Gragert L, Khalil K, Camellato B, Faria de Oliveira M, O’Brien D, Weldon E, Lin X, Gao H, Kagermazova L, Kim J, Loupy A, Heguy A, Taylor S, Zhu F, Gao S, Gandla D, Reddy K, Chang A, Michael B, Jiang L, Jian R, Narula N, Linna-Kuosmanen S, Kaikkonen-Määttä M, Lorber M, Kellis M, Tatapudi V, Ayares D, Griesemer A, Mangiola M, Pass H, Snyder MP, Montgomery RA, Boeke JD, Keating BJ (2024) Integrative Multi-omic Profiling of Two Human Decedents Receiving Pig Heart Xenografts Reveals Strong Perturbations in Early Immune-Cell and Cellular Metabolism Responses. Nature Medicine 2024 May 17. doi: 10.1038/s41591-024-02972-1.
  • Crane C, Niemann M, Dale B, Gragert L, Shah M, Ingulli E, Morris GP. (2024) High-resolution HLA genotyping improves PIRCHE-II assessment of molecular mismatching in kidney transplantation. Human Immunology 2024 May 14:110813. doi: 10.1016/j.humimm.2024.110813.
  • Scorr LM, Kilic-Berkmen Gamze, Sutcliffe DJ, Dinasarapu AR, McKay JL, Bagchi P, Powell MD, Boss JM, Cereb N, Little M, Gragert L, Hanfelt J, McKeon A, Tyor W, Jinnah HA. (2024) Exploration of potential immune mechanisms in cervical dystonia. Parkinsonism & Related Disorders 2024 Feb 17:106036. doi: 10.1016/j.parkreldis.2024.106036.
  • Lim WC, Marques da Costa ME, Godefroy K, Jacquet E, Rondof E, Gragert L, Nhiri N, Dalfovo D, Viard M, Labaied N, Khan MA, Dessen P, Romanel A, Pasqualini C, Schleiermacher G, Carrington M, Zitvogel L, Scoazec JY, Geoerger B, Salmon J. (2023) Divergent HLA Variations and Heterogeneous Expression but Recurrent HLA Loss-of-Heterozygosity and Common HLA-B and TAP Transcriptional Silencing Across Advanced Pediatric Solid Cancers. Frontiers in Immunology Vol 14 DOI: 10.3389/fimmu.2023.1265469.
  • Ferar K, Hall TO, Crawford DC, Rowley R, Satterfield BA, Li R, Gragert L, Karlson EW, de Andrade M, Kullo IJ, McCarty CA, Kho A, Hayes MG, Ritchie MD, Crane PK, Mirel DB, Carlson C, Connolly JJ, Hakonarson H, Crenshaw AT, Carrell D, Luo Y, Dikilitas O, Denny JC, Jarvik GP, Crosslin DR. (2023) Genetic variation in the human leukocyte antigen region confers susceptibility to Clostridioides difficile infection. Scientific Reports 13:18532.
  • Israeli S, Gragert L, Madbouly A, Bashyal P, Schneider J, Maiers M, Louzoun Y. (2023) Combined imputation of HLA genotype and self-identified race leads to better donor-recipient matching. Human Immunology 84(12):110721. Li F, Gragert L, Biagini DG, Patel JK, Kobashigawa J, Trück J, Rodriguez O, Watson CT, Gibb D, Zhang X, Kransdorf EP. (2023) IgM Marks Persistent IgG Anti-Human Leukocyte Antigen Antibodies in Highly Sensitized Heart Transplant Patients. Journal of Heart and Lung Transplantation 2023 Oct 2:S1053-2498(23)02055-7. PMID: 37793509.
  • Han J, Rushakoff J, Moayedi Y, Henricksen E, Lee R, Luikart H, Shalakthi O, Gragert L, Benck L., Malinowski D, Kobashigawa J., Teuteberg J, Khush K, Patel J, Kransdorf EP (2023) HLA sensitization is associated with an increased risk of primary graft dysfunction after heart transplantation. Journal of Heart and Lung Transplantation 2023 Oct 4:S1053-2498(23)02030-2. PMID: 37802261.
  • Johnson AC, Zhang J, Gragert L, Hertzberg V, Larsen, CP (2023) Belatacept with Time-limited Tacrolimus Co-immunosuppression Modifies the 3-year Risk of Eplet Mismatch in Kidney Transplantation. American Journal of Transplantation 2023 Sep 29;S1600-6135(23)00699-8. PMID: 37778459 DOI:10.1016/j.ajt.2023.09.011
  • Mack SJ, Schefzyk D, Milius RP, Maiers M, Hollenbach JA, Pollack J, Heuer ML, Gragert L, Spellman SR, Guethlein LA, Schneider J, Bochtler W, Eberhard HP, Robinson J, Marsh SGE, Schmidt AH, Hofmann JA, Sauter J (2023) Genotype List String 1.1: Extending the Genotype List String Grammar for Describing HLA and Killer-cell Immunoglobulin-like Receptor Genotypes. HLA: Immune Response Genetics DOI: 10.1111/tan.15126

  • Dasariraju S, Gragert L, Wager G, McCullough K, Brown NK, Kamoun M, Urbanowicz R. (2023) HLA Amino Acid Mismatch-Based Risk Stratification of Kidney Allograft Failure Using a Novel Machine Learning Algorithm. Journal of Biomedical Informatics Available online 27 April 2023, 104374. DOI: 10.1016/j.jbi.2023.104374.

  • Ansbacher-Feldman Z, Israeli S, Maiers M, Gragert L, De Santis D, Israeli M, Louzoun Y. (2023) GRAMM – a new method for analysis of HLA in families. HLA: Immune Response Genetics DOI: 10.1111/tan.15075

  • Nilsson J, Kaabinejadian S, Yari H, Peters B, Barra C, Gragert L, Hildebrand W, Nielsen M. (2023) Machine learning reveals limited contribution of trans-only encoded variants to the HLA-DQ immunopeptidome by accurate and comprehensive HLA-DQ antigen presentation prediction. Communications Biology 6(1) 442.

  • Narayan R, Niroula A, Wang T, Kuxhausen M, He M, Meyer E, Chen YB, Bhatt VR, Beitinjaneh A, Nishihori T, Sharma A, Brown VI, Kamoun M, Diaz MA, Abid MB, Askar M, Kanakry CG, Gragert L, Bolon YT, Marsh SGE, Gadalla SM, Paczesny S, Spellman S, Lee SJ (2023) HLA Class I genotype is associated with relapse risk after allogeneic stem cell transplantation for NPM1-mutated AML. Transplantation and Cellular Therapy DOI: 10.1016/j.jtct.2023.03.027.

  • Kim JJ, Fichtner A, Copley HC, Gragert L, Süsal C, Strologo LD, Oh J, Pape L, Weber LT, Weitz M, König JC, Krupka K, T Burkhard, Kosmoliaptsis V (2023) Molecular HLA mismatching for prediction of primary humoral alloimmunity and graft function deterioration in paediatric kidney transplantation. Frontiers in Immunology 14:1092335.

  • Gragert L, Spellman S, Shaw B, Maiers M. (2023) Unrelated Stem Cell Donor HLA Match Likelihoods in the US Registry Incorporating HLA-DPB1 Permissible Mismatching. Transplantation and Cellular Therapy 29(4) 244-252.

  • Stahl M, Li Q, Lynch K, Koletzko S, Mehta P, Gragert L, Norris J, Aronsson C, Lindfors K,  Kurppa K, Ilonen J, Krischer J, Alkolkar B, She J, Ziegler A, Toppari J, Rewers M, Agardh D, Hagopian, W, Liu E, and the TEDDY Study Group. (2022) Incidence of Pediatric Celiac Disease Varies by Region. American Journal of Gastroenterology 118(3):539-545.

  • Olson T, Frost BF, Duke JL, Dribus M, Xie HM, Prudowsky ZD, Furutani E, Gudera J, Shah Y, Ferriola D, Xu E, He M, Zheng S, Nijim S, Lin P, Xu C, Nakano T, Oved JH, Carreno BM, Lee SJ, Monos DS, Shimamura A, Bertuch AA, Gragert
    L,
    Spellman SR, Babushok D (2022) Pathogenicity and impact of HLA class I alleles in aplastic anemia patients of different ethnicities. JCI Insight e163040.

  • Gragert L, Kadatz M, Alcorn J, Stewart D, Gill J, Liwski R, Gebel H, Gill J, Lan J. (2022) ABO-Adjusted Calculated Panel Reactive Antibody (cPRA): A Unified Metric for Immunologic Compatibility in Kidney Transplantation. American Journal of Transplantation. doi: 10.1111/ajt.17175. PMID: 35975734

 

 

 

 

  • Sajulga R, Madbouly A, Fingerson S, Gragert L, Bashyal P, Bolon YT, Maiers M. (2021) Predicting HLA-DPB1 Permissive Probabilities through a DPB1 Prediction Service towards the Optimization of HCT Donor Selection. Human Immunology 82(21) 903-911. PMID: 34362573

 

 

 

  • Kransdorf E, Pando M, Stewart D, Lindblad K, Patel J, Kim I, Zhang X, Maiers M, Kobashigawa J, Gragert L. (2021) Stem Cell Donor HLA Typing Improves CPRA in Kidney Allocation. American Journal of Transplantation 21(1) 138-147. PMID: 32558252

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Reviews, Commentary, and Consensus Reports:

 

  • Gragert L. (2022) A Template for Multitudes: Germline immune polymorphism of the T cell receptor loci. Cell Genomics 2(12) 100231.
  • Yu N, Askar M, Wadsworth K, Gragert L, Fernandez-Vina M. (2022) Current HLA Testing recommendations to support HCT. Human Immunology 83(10) 665-673.
  • Kransdorf EP, Pando MJ, Gragert L, Kaplan B. HLA Population Genetics in Solid Organ Transplantation . Transplantation. 2017; 101(9):1971-1976. PMID: 28832450

Book Chapters and Government Reports:

  • Organ Procurement and Transplantation Network (OPTN) Public Comment Proposal – “Change Calculated Panel Reactive Antibody (CPRA) Calculation”. Public Comment Period: January 27, 2022-March 23, 2022. https://optn.transplant.hrsa.gov/policies-bylaws/public-comment/change-calculated-panel-reactive-antibody-cpra-calculation/
  • Petz LD, Spellman S, Gragert L. Cord Blood: Biology, Transplantation, Banking, and Regulation. Broxmeyer H, editor. Bethesda, MD: AABB Press; 2011. Chapter 32, The Underutilization of Cord Blood Transplantation: Extent of the Problem, Causes, and Methods of Improvement; p.557-584. 714p.
  • Howard DH, Maiers M, Kollman C, Logan B, Gragert L, Setterholm, M. Cord Blood – Establishing a National Hematopoietic Stem Cell Bank Program. Meyer EA, Hanna K, Gebbie K, editors. Washington, DC: Institute of Medicine of the National Academies: The National Academies Press; 2005. Chapter Appendix E, A Cost-Benefit Analysis of Increasing Cord Blood Inventory Levels; p.221-241. 314p. https://www.nap.edu/read/11269/chapter/14

 

Trade / Society Publications:

  • Gragert L. (2024) My Life in HLA. ASHI Quarterly 48(1) 22-23.
  • Gragert L. (2021) Progress Towards a Comprehensive Calculated Panel Reactive Antibody (CPRA) Calculator Based on Stem Cell Registry Typing Data. ASHI Quarterly 45(4) 31-33.
  • Gragert L. (2019) A New Tool for Interpreting Molecular HLA Typing Data for Entry into UNet. ASHI Quarterly 42(4) 30-31.